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USP18 bound to JAK1 inhibits Interferon. 1 / 1

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"Based on mutational studies it was suggested that USP18 binds to the intracellular region of type I IFN receptor subunit IFNAR2 and outcompetes the downstream kinase JAK1 thereby abrogating IFN signaling XREF_BIBR."

28165509

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USP18 bound to JAK1 inhibits Interferon. 1 / 1

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