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OTUB1 activates p53S46P. 2 / 2

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"Knockdown of MDMX reduced Otub1 induced p53S46P, which was shown to be critical for p53 's mitochondrial function and apoptotic activity."

28035068

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"Together, these results suggest that Otub1 stabilizes MDMX and promotes p53S46P and mitochondria mediated apoptosis, providing an alternative mechanism of Otub1 's role in apoptosis."

28035068

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IndraLab

Statements

OTUB1 activates p53S46P. 2 / 2

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