IndraLab

Statements

TRAIP binds USP37. 7 / 7
| 1 6
reach
"We propose that this regulation is critical to allow the completion of DNA replication and the suppression of genome instability.We uncovered a complex genetic interaction between USP37 and TRAIP."
39282314
sparser
"While TRAIP knockout and USP37 knockout cells were hypersensitive to camptothecin, as expected xref , xref , the USP37-TRAIP double knockout cells largely lost their hypersensitivity towards camptothecin (Fig. xref and Supplementary Fig. xref ), indicating that TRAIP loss compensates for the absence of USP37 and vice versa."
40533495
sparser
"While TRAIP knockout and USP37 knockout cells were hypersensitive to CPT, as expected xref , xref , the USP37-TRAIP double knockout cells largely lost their hypersensitivity towards CPT ( xref and xref ), indicating that TRAIP loss compensates for the absence of USP37 and vice versa."
39282314
sparser
"While both TRAIP knockout and USP37 knockout cells had elevated levels of stalled forks that failed to restart, USP37-TRAIP knockout reduced fork stalling to the level seen in WT cells after camptothecin washout (Supplementary Fig. xref )."
40533495
sparser
"We uncovered a complex genetic interaction between USP37 and TRAIP ."
40533495
sparser
"Our observations in Xenopus egg extracts help explain the genetic interaction between TRAIP and USP37."
40533495
sparser
"We uncovered a complex genetic interaction between USP37 and TRAIP ."
39282314