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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

PRPF8 activates intein-mediated protein splicing. 1 / 1

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reach

"The recent discovery of a small molecule inhibitor of the Prp8 intein that selectively inhibits splicing without targeting proteases and inhibits the growth of intein-containing C. gattii and C. neoformans is a particularly exciting breakthrough that suggests intein inhibitors may have therapeutic benefits (Li et al., 2021)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...