IndraLab

Statements

(+)-alpha-tocopherol inhibits IKBKB. 2 / 2
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"Moreover, TNF-alpha-enhanced IKK-beta activity was also inhibited by (polyethylene glycol) PEG-catalase, N-acetylcysteine (NAC), and vitamin E."
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"Moreover, vitamin E deficiency down-regulated antimicrobial peptides (Hepcidin, liver expressed antimicrobial peptide-2A, -2 B, beta-defensin), IL-10, TGFbeta1, IkappaBalpha, TOR and S6K1 mRNA levels (P < 0.05) and up-regulated IL-1beta, IL-6, IL-8, IFN-gamma2 and TNFalpha, NF-kappaB p65, IKKalpha, IKKbeta and 4EBP1 (not in the head kidney) mRNA levels (P < 0.05)."
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