IndraLab

Statements



reach
"Although we do not find a clear role for USP42 in controlling either the basal or fully activated levels of p53, the function of USP42 is required to allow the rapid activation of p53 dependent transcription and a p53 dependent cell-cycle arrest in response to stress."

reach
"Again, we found three examples of genes that were not significantly affected by USP42 depletion (TAp73, FOXM1, and CCNE1), indicating that the requirement for USP42 to promote transcription is not universal."