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1,2-dioleoyl-sn-glycero-3-phospho-L-serine inhibits NLRP3. 5 / 5
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"They also examined whether DOPS administration might significantly reduce the activation of the NLRP3 inflammasome and the β-arrestin1 signaling pathways."
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"The findings revealed that DOPS could suppress NLRP3 inflammasome pathways, reflected by inhibiting the activation of NLRP3 inflammasome, cleavage of caspase1, and production of IL-1β and IL-18.In add[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"According to our previous study, DOPS could inhibit the activation of NLRP3 inflammasome signaling pathways, which indicated an improtant role in enhancing the intestinal barrier function."
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"We further explored whether DOPS could inhibit the activation of NLRP3 inflammasome and β-arrestin1 signaling pathways in vitro ."
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"Consistently, DOPS treatment strongly decreased the staining of NLRP3 and β-arrestin1 in LPS-stimulated NCM460 cells ( Fig. 8 A–D)."
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