IndraLab
Statements
reach
"Although TANs do not seem to be implicated in the phagocytosis mechanism of rituximab activity [XREF_BIBR], in vitro and in vivo studies, have demonstrated that TANs may compromise the cytotoxic effect of common chemotherapeutic agents used through CD11b and ICAM -1 interaction with CD44 of malignant B cells and inhibit FL B cell apoptosis."