IndraLab

Statements

YOD1 decreases the amount of PML. 2 / 2

| 2

reach

"In line with these results, YOD1 also notably downregulated the ubiquitination levels of drug-resistant PML/RARα mutants (ΔF286, R276Q, L218P and A216V) (Fig. 3E), strongly supporting that YOD1 may deubiquitination of PML/RARα."

35847510

➶

reach

"These results strongly indicate that YOD1 functions as a critical regulator for the ubiquitination proteasome pathway-dependent degradation of PML/RARα.3.2 YOD1 silencing decreases the protein levels of drug-resistant PML/RARalpha mutants."

35847510

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

YOD1 decreases the amount of PML. 2 / 2

INDRA sources:

Databases

Reading