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UCHL3-C95S increases the amount of Proteasome. 1 / 1

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"To address whether UCHL3 C95S impedes Ub(G76V)‐GFP turnover at the level of p97 or the proteasome, we employed a variant Ub(G76V)‐GFP protein containing a C‐terminal 20‐amino acid extension (Ub(G76V)‐GFP‐20AA), which has been shown to override the requirement for p97‐mediated unfolding to enable its proteasomal degradation (Beskow et al, 2009; Godderz et al, 2015) (Fig 5E)."

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IndraLab

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UCHL3-C95S increases the amount of Proteasome. 1 / 1

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