IndraLab

Statements

Simvastatin inhibits CASP1. 4 / 5
1 | 4
reach
"Simvastatin inhibits GBM progression by suppressing caspase-1 dependent pyroptosis, regulated by miR-214."
35342027
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"Our results show that statin lowering of prenylation isoprenoids activate caspase-1 and IL-1beta inflammasome responses that impair endocrine control of adipocyte lipogenesis."
31010959
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"However, in U87 and U251 glioma cells, simvastatin inhibited pyroptosis and caused cell death by inhibiting caspase-1, NLRP3, and IL-1β production."
36867378
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"Wang et al. have found that simvastatin suppressed the A549 and H1299 NSCLC cells proliferation and migration via caspase-1 dependent pyroptosis [45] ."
34217831