IndraLab

Statements

OPTN inhibits CYLD. 2 / 2

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"Of note, optineurin, a gene in one of the other Paget 's susceptibility loci can also attenuate TNF-alpha signaling by recruiting CYLD to RIP1."

25025000

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reach

"In conclusion, our observations strongly suggest that optineurin mediates targeting of CYLD to its substrate (i.e ubiquitinated RIP) which facilitates its deubiquitination."

21408173

INDRA sources:

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IndraLab

Statements

OPTN inhibits CYLD. 2 / 2

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