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USP12 deubiquitinates TCR. 2 / 2

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"Recently, USP12 was shown to stabilize the TCR complex at the cell surface by deubiquitinating TCR adaptor proteins LAT and Trat1."

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"Similarly, the ubiquitin specific peptidase 12 (USP12) can deubiquitinate LAT at the proximal TCR (Figure 2), to protect it from ubiquitin-dependent lysosomal degradation [146]."

| PMC

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USP12 deubiquitinates TCR. 2 / 2

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