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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

THBS1 binds ANXA6 and LRP1. 3 / 3

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"Nevertheless, further studies are required to validate whether the ANXA6, LRP1, and TSP1 complex may enter exosomes to support the aggressiveness of PaCa."

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"Increased PDA aggressiveness was dependent on tumor cell mediated uptake of CAF derived ANXA6+ EVs carrying the ANXA6, LRP1, and TSP1 complex."

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"Formation of the ANXA6, LRP1, and TSP1 complex was restricted to cancer associated fibroblasts (CAFs) and required physiopathologic culture conditions that improved tumor cell survival and migration."

27701147

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Statements

THBS1 binds ANXA6 and LRP1. 3 / 3

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