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RyR activates CACNA1A. 1 / 1
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"It has been shown that in addition to the II-III loop of the DHPR, which may modulate transverse tubular voltage–dependent RyR activation ( xref , xref ), Ca 2 + release from RyR in skeletal muscle is modulated by endogenous ligands such as Ca 2 + and Mg 2 + ( xref ; xref ; xref ) as well as regulatory proteins such as calmodulin and FKBP12 ( xref ; xref ; xref )."