IndraLab

Statements

USP35 activates ESR1. 3 / 3
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"Similar effects have been observed in breast cancer, where USP35 enhances tumorigenesis by stabilizing estrogen receptor α (ERα), leading to increased proliferation and metastasis [37]."
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"For example, USP35 promotes tumorigenesis in estrogen receptor (ER)-positive breast cancer by stabilizing and activating estrogen receptor α (Erα) to increases Erα transcriptional activity [19]."
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"USP35, regulated by estrogen and AKT, promotes breast tumorigenesis by stabilizing and enhancing transcriptional activity of estrogen receptor alpha."
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