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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP12 activates lipopolysaccharide. 2 / 2

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"Deubiquitinase USP12 promotes LPS induced macrophage responses through inhibition of IkappaBalpha."

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"Most of the deubiquitinases, including A20 and CYLD, can inhibit NF-kappaB activation [XREF_BIBR], while USP12 positively regulates the LPS signal [XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...