IndraLab

Statements


| 5 9

sparser
"We found that USP33(△DSG) can also interact with β-TrCP ( Fig. 3 B )."

reach
"We found that USP33 (^ DSG) can also interact with beta-TrCP."

sparser
"Furthermore, we found that the WD40 motif of β-TrCP and 201-400 amino acid motif of USP33 are required for the interaction between β-TrCP and USP33."

reach
"Beta-TrCP can also interact with FH-USP33 (^ DSG), indicating that the interaction between beta-TrCP and USP33 is independent of DSG motif of USP33."

sparser
"Our data showed that USP33 was able to interact with β-TrCP-WT, but unable to interact with β-TrCP-△WD40 ( Fig. 3 D )."

sparser
"Collectively, we found that the WD40 motif of β-TrCP and 201–400 amino acid motif of USP33 are necessary for the interaction between β-TrCP and USP33."

sparser
"Β-TrCP is able to interact with USP33, and promotes the ubiquitination and proteasomal degradation of USP33."

reach
"These results suggest that the effect of beta-TrCP on USP33 is independent of the classic DSG motif.Since beta-TrCP promotes USP33 ubiquitin dependent degradation, then we assessed the interaction bet[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"The interaction of β-TrCP with these USP33 mutants was evaluated."

reach
"We also revealed that beta-TrCP interacted with USP33 independently of the classic binding motif for beta-TrCP, and mediated USP33 degradation via the ubiquitin proteasome pathway."

sparser
"Co-immunoprecipitation assays showed that β-TrCP was able to interact with endogenous USP33 ( Fig. 3 A )."

sparser
"Since β-TrCP promotes USP33 ubiquitin-dependent degradation, then we assessed the interaction between β-TrCP and USP33."

reach
"Furthermore, we found that the WD40 motif of beta-TrCP and 201-400 amino acid motif of USP33 are required for the interaction between beta-TrCP and USP33."

sparser
"Β-TrCP can also interact with FH-USP33(△DSG) ( Fig. 3 B ), indicating that the interaction between β-TrCP and USP33 is independent of DSG motif of USP33."