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OTUD6A binds NLRP3. 1 / 1

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"These findings are consistent with the work of Xin Liu et al. [ xref ], which showed that OTUD6A directly bound to the NACHT domain of the NLRP3 inflammasome and selectively cleaved K48-linked polyubiquitin chains from NLRP3 at K430 and K689 to enhance the stability of NLRP3, leading to increased Il1β levels and inflammation [ xref ]."

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IndraLab

Statements

OTUD6A binds NLRP3. 1 / 1

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