IndraLab

Statements

CALM1 binds CACNA1C. 6 / 7
1 | 6
sparser
"These six LR interactions, namely APOE-SORL1, APOE-LRP1, CALM1-CACNA1C, CALM1-RYR2, CALM3-CACNA1C, and CALM3-RYR2 (Fig.  xref c, d), consistently exhibited downregulation patterns in AD in comparative intercellular communication analysis."
38167548
sparser
"Among them, ten LR gene pairs ( CALM1-GRM5, CALM1-GRM7, CALM1-RYR2, CALM-GRM5, and CALM3-GRM7, CALM3-RYR2, CALM1-CACNA1C, CALM3-CACNA1C, CALM3-EGFR, CALM3-INSR ) were prioritized in the pathway analyses."
37790454
sparser
"Among them, ten LR gene pairs ( CALM1-GRM5, CALM1-GRM7, CALM1-RYR2, CALM3 -GRM3, and CALM5-GRM7, CALM3-RYR2, CALM1-CACNA1C, CALM3-CACNA1C, CALM3-EGFR, CALM3-INSR ) were prioritized in the pathway analyses (Additional file xref : Table S6)."
38167548
sparser
"Our pathway analyses highlighted biological functions—such as regulation of calcium ion transport, second messenger-mediated signaling, and maintenance of location, which encompass four dysregulated LR pairs, including CALM1-RYR2, CALM3-RYR2, CALM1-CACNA1C, CALM3-CACNA1C ( xref , Additional file 6: Table S5)."
37790454
sparser
"Our pathway analyses highlighted GO BPs—such as regulation of calcium ion transport, second messenger-mediated signaling, and maintenance of location, which encompass four dysregulated LR pairs, including CALM1-RYR2, CALM3-RYR2, CALM1-CACNA1C, and CALM3-CACNA1C (Fig.  xref , Additional file xref : Table S6)."
38167548
sparser
"Comparing C2 to C1, the top enriched L-R pairs included Lamc1-Itgb1 , Calm1-Cacna1c , Lamc1-Itga6 , and Ntn1-Unc5b ."
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