IndraLab

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Modified USP7 leads to the deubiquitination of TP53. 2 / 2

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"As shown in XREF_FIG, Mdm2 induced the ubiquitination of p53; however, p53 ubiquitination was significantly diminished by coexpression of USP10 or HAUSP."

20096447

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"There also seems to be a delicate balance between these proteins, as a modest reduction of HAUSP levels prevents p53 deubiquitination but complete ablation of HAUSP causes robust p53 stabilization."

20404858

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IndraLab

Statements

Modified USP7 leads to the deubiquitination of TP53. 2 / 2

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