IndraLab

Statements

Sodium_channels binds SCN9A. 3 / 3
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"Some of these sodium channels—Nav1.7, Nav1.8, and Nav1.9—are also involved in pain sensation, and blocking these channels could help develop nonaddictive painkillers. “Because of the opioid crisis in the United States there is an urgent need for a new generation of painkillers, and these are very promising targets,” says Yan."
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"For example, one study suggested that the SCN9A gene-encoded dorsal root ganglia sodium channel polymorphism was associated with severe symptoms of FM. xref "
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"The SCN9A gene, which encodes the Nav1.7 voltage-gated sodium channel, is associated with different abnormal pathophysiological conditions, such as human pain sensitivity xref , xref ."
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