IndraLab

Statements


| 1 3

reach
"Recent initial applications of PTM analysis to CAVD revealed that nitric oxide modulates S-nitrosylation of the deubiquitinase USP9X and controls anti-calcific NOTCH in cultured VICs."

reach
"NO activates USP9X to deubiquitinate MIB1."

eidos
"Together , these data indicate that NO activates USP9X by S-nitrosylation , which deubiquitinates and stabilizes MIB1 , and this is followed by the activation of NOTCH1 signaling to prevent calcification ."

reach
"Together, these data indicate that NO activates USP9X by S nitrosylation, which deubiquitinates and stabilizes MIB1, and this is followed by the activation of NOTCH1 signaling to prevent calcification."