IndraLab

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"The results revealed that YOD1 knockdown markedly enhanced the growth of subcutaneous tumors (Fig. 1J–L) and the incidence of lung metastasis (Fig. 1M, N) in nude mice and NCG mice."

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"Notably, YOD1 knockdown significantly promoted the proliferation of tumor organoids derived from ccRCC patients (Fig. 2G)."

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"Conversely, increased YOD1 expression blocks ERK signaling by stabilizing TRIM33 activation, thereby inhibiting tumor invasion and lymph node metastasis in squamous cell carcinoma of the head and neck [25]."

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"In another study, overexpression of YOD1 abrogated miR-373-induced cervical cancer progression, including cell proliferation, colony formation in vitro as well as tumor growth assays in vivo [ 17 ]."

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"Knockdown of YOD1 markedly promoted subcutaneous tumor growth (Fig. 7H–J) and lung metastasis (Fig. 7K, L), and these effects were reversed by ZNF24 overexpression."

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"Moreover, YOD1 knockdown promoted tumor growth and metastasis in vitro and in vivo."

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"Overexpression of YOD1 attenuates tumor growth and lymph node metastasis of HNSCC cells in vivo."

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"Deubiquitinase YOD1 suppresses tumor progression by stabilizing E3 ligase TRIM33 in head and neck squamous cell carcinoma."

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"The deubiquitinase YOD1 suppresses tumor progression by stabilizing ZNF24 in clear cell renal carcinoma."