IndraLab

Statements

ATP1A1 activates TRPV1. 4 / 4
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"We observed that NA directly and potently activates TRPV1 from the intracellular side by lowering the activation threshold for heat, causing channel activation at physiological body temperature."
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"In a recent study xref , we found that NA activates the capsaicin receptor TRPV1, a heat-activated polymodal cellular sensor that mediates the flushing response upon consumption of spicy food xref xref ."
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"Our observation of NA-induced TRPV1 activation raises the question whether these TRPV1 homologs can also be targeted by NA."
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"Our reported study showed that NA directly and strongly activates TRPV1 from the intracellular side xref ."
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