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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

UCHL1 increases the amount of HIF1A. 2 / 2

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"In addition to such a molecular mechanism, we recently revealed the possibility that UCHL1 increases the expression levels of HIF-1alpha by upregulating the efficiency of the transcriptional initiation of the HIF-1alpha gene (data not shown)."

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"Western blotting consistently showed that the UCHL1 dependent increase in HIF-1alpha protein levels was only observed in the presence of VHL (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...