IndraLab

Statements

CACNA1C binds egfp. 4 / 4
| 4
sparser
"As in human cells, responder granules were associated with stronger EGFP-CaV1.2 signals than were failures (ΔF/S = 0.10 ± 0.02 versus 0.006 ± 0.001, n = 91 granules, 18 cells; P = 0.0003) ( xref )."
28481223
sparser
"When either the II–III loop fragment or the C2 domain of Munc13-1 was coexpressed, EGFP-CaV1.2 still formed clusters in the plasma membrane ( xref ), but its binding to granules (ΔF/S) was strongly reduced ( xref )."
28481223
sparser
"By dividing this value with the fluorescence of a single EGFP molecule (0.82 ± 0.01 × 10 6 cu/(W × s); xref ), we derived that, on average, 2.4 ± 0.4 EGFP-CaV1.2 molecules bound to each granule."
28481223
sparser
"The average ΔF value in the experiments depicted in xref , is proportional to the copy number of EGFP-CaV1.2 molecules that are bound to the average granule site."
28481223