IndraLab

Statements

USP28 activates glycolytic process. 8 / 8
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"In conclusion, USP28 enhanced cell viability and aerobic glycolysis of colorectal cancer by stabilizing FOXC1, suggesting that USP28-FOXC1 might be a novel therapeutic avenue for colorectal cancer."
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"USP28 promotes tumor progression and glycolysis by stabilizing PKM2/Hif1-α in cholangiocarcinoma."
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"USP28 increases aerobic glycolysis and promotes cell proliferation upon stabilization of FOXC1 [50]."
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"In addition to promoting the cell cycle and enhancing aerobic glycolysis, USP28 can also stimulate cell proliferation."
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"USP28 promotes aerobic glycolysis of colorectal cancer by increasing stability of FOXC1."
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"After stabilizing FOXC1, USP28 enhances aerobic glycolysis and promotes cell proliferation."
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"Ubiquitin-specific protease 28 (USP28) can promote glycolysis through mediating PKM2, which in turn promotes the progression of Cholangiocarcinoma [37]."
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"Functional assays demonstrated that overexpression of USP28 promoted cell proliferation and aerobic glycolysis of colorectal cancer, while USP28 inhibition could reverse these effects."
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