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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP28 activates glycolytic process. 4 / 4

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"Functional assays demonstrated that overexpression of USP28 promoted cell proliferation and aerobic glycolysis of colorectal cancer, while USP28 inhibition could reverse these effects."

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"USP28 increases aerobic glycolysis and promotes cell proliferation upon stabilization of FOXC1 [50]."

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"USP28 promotes aerobic glycolysis of colorectal cancer by increasing stability of FOXC1."

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"In conclusion, USP28 enhanced cell viability and aerobic glycolysis of colorectal cancer by stabilizing FOXC1, suggesting that USP28-FOXC1 might be a novel therapeutic avenue for colorectal cancer."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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USP28 activates glycolytic process. 4 / 4

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