IndraLab

Statements

USP28 activates glycolytic process. 4 / 4
| 4
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"Functional assays demonstrated that overexpression of USP28 promoted cell proliferation and aerobic glycolysis of colorectal cancer, while USP28 inhibition could reverse these effects."
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"USP28 increases aerobic glycolysis and promotes cell proliferation upon stabilization of FOXC1 [50]."
| PMC
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"USP28 promotes aerobic glycolysis of colorectal cancer by increasing stability of FOXC1."
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"In conclusion, USP28 enhanced cell viability and aerobic glycolysis of colorectal cancer by stabilizing FOXC1, suggesting that USP28-FOXC1 might be a novel therapeutic avenue for colorectal cancer."
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