IndraLab

Statements


KCNH2 activates Lys-Ser. 2 / 2
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"However, the presence of WT HERG decreased the deactivation time constant for I Ks and the presence of G816V HERG decreased the I Ks time constant to a greater degree (XREF_FIG)."

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"Mutations in the KCNQ1 and HERG genes cause the Long QT Syndromes, LQTS1 and LQTS2, due to reductions in the cardiac repolarizing I Ks and I Kr currents, respectively."