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USP33 leads to the deubiquitination of TGFBP2. 1 / 1
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"USP33 can promote TGFBP2 deubiquitination and TGF-β activation, which, in turn, targets Zeb1 to trigger the transcription of USP33, thus forming a positive feedback loop to stimulate PDAC metastasis (Liu et al., 2023c)."