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Ruboxistaurin inhibits KCNH2. 1 / 1

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"Further in vitro experiments indicated that ruboxistaurin is able to block the hERG channel (human ether-a-go-go related gene) with an IC 50 of 35.6 nM, altering the repolarization of the myocardium and potentially contributing to the observed QTc prolongation [XREF_BIBR]."

30742812

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IndraLab

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Ruboxistaurin inhibits KCNH2. 1 / 1

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