IndraLab

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USP36 increases the amount of MYC. 4 / 4
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"Consistently, knockdown of USP36 reduces the levels of c-Myc and suppresses cell proliferation."
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"The overexpression of USP36 increased c-Myc protein level in ischemia treated HK-2 cells, without affecting its mRNA level."
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"Previous studies have established that overexpression of Wild-type USP36, but not the catalytic-inactive C131A mutant, deubiquitinated c-Myc and increased the levels of endogenous c-Myc in vitro [ 20 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The depletion of USP36 dramatically decreases c-Myc levels as previously described [ 20 ] ( Fig. 3 D)."
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