IndraLab

Statements

USP15 activates RELA. 2 / 2
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reach
"Our findings suggest that miR-181a-5p-containing MSC-EVs can influence neurodegeneration and inflammation in EAE by inhibiting microglial pyroptosis through the USP15-mediated RelA/NEK7 axis, providin[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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reach
"Further, CSN-associated USP15 directs deubiquitylation and stabilization of CRL-substrate IκBα, whereas CSN-associated USP48 stabilizes the nuclear pool of RelA, thereby facilitating timely induction and shutoff of NF-κB target genes."
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