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Statements

USP15 activates Fibrosis. 2 / 2
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"Hepatocyte deletion of USP15 suppresses liver steatosis, inflammation, and fibrosis in mouse models of NASH."
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"Researchers discovered that The expression of the deubiquitinating enzyme USP15 is upregulated in the livers of HFD-fed mice and in liver biopsy tissues from patients with NAFLD or NASH, whereas hepatocyte deletion of USP15 suppresses hepatic steatosis, inflammation, and fibrosis in a mouse model of NASH (133)."
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