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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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UCHL1 inhibits MITF. 3 / 4

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"Therefore, the present finding that UCHL1 can suppress MITF activity might serve as the basis for further studies conducted to evaluate new therapeutic approaches for melanoma and dyspigmentation diso[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In parallel, UCHL1 dependent degradation of MITF was observed in the total cell lysates (input)."

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"Indeed, overexpression of UCHL1 significantly increased the degradation of MITF protein (P < 0.05)."

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Statements

UCHL1 inhibits MITF. 3 / 4

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