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UCHL1 inhibits MITF. 3 / 4
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"Therefore, the present finding that UCHL1 can suppress MITF activity might serve as the basis for further studies conducted to evaluate new therapeutic approaches for melanoma and dyspigmentation diso[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In parallel, UCHL1 dependent degradation of MITF was observed in the total cell lysates (input)."

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"Indeed, overexpression of UCHL1 significantly increased the degradation of MITF protein (P < 0.05)."