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TP53 phosphorylated on S15 increases the amount of TP53. 3 / 3
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"Recent studies suggest that the p53- and GR-mediated pathways are linked, with GR-activation leading to the phosphorylation of p53 at ser-15, which activates p53-mediated transcription of the cyclin-d[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"ultimate carcinogen benzo[a]pyrene diol epoxide (BPDE) Analyses of proteins in treated cells indicated that p53 was phosphorylated at Ser15 but not at Ser20 within 30 min of treatment, and this correlated with an increase in the total amount of p53 protein."
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"Further, Ser-15 phosphorylation of p53 may contribute to increased levels of p53 protein (Figure 4D)."
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