IndraLab

Statements

RNF41 ubiquitinates USP8. 8 / 8
1 | 1 4 2
reach
"NRG1-mediated ubiquitination and degradation of USP8 can be abrogated by knockdown of Nrdp1 or USP8 in breast cancer cells [95] ."
36872193
reach
"The RNF41 promotes USP8 ubiquitination and degradation whereas the USP8 promotes removing the ubiquitin from RNF41 and thus stabilize it."
33600786
sparser
"The deubiquitinase USP8 stabilizes the E3 ligase RNF41, and RNF41 in turn ubiquitinates and destabilizes USP8 to regulate LepR degradation [ xref ]."
37724323
reach
"The deubiquitinase USP8 stabilizes the E3 ligase RNF41, and RNF41 in turn ubiquitinates and destabilizes USP8 to regulate LepR degradation [165]."
37724323
signor
"RNF41 redistributes and ubiquitylates USP8, and reduces USP8 levels."
23750007
sparser
"We further demonstrated that this results from RNF41-dependent ubiquitination and suppression of the deubiquitinating enzyme USP8, which abrogates ESCRT-0 functionality and accounts for the rerouting of cytokine receptors ( xref )."
28270795
trips
"RNF41 redistributes and ubiquitylates USP8, and reduces USP8 levels."
23750007
reach
"Mechanistically, the E3 ligase Nrdp1 indirectly destabilizes the ESCRT-0 complex by ubiquitinating and suppressing USP8."
31845722