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TARDBP activates ATXN3. 1 / 1

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"Knocking down TDP-43 in HeLa cells induced apoptosis via the upregulation of cyclin dependent kinase 6 (cdk6) [XREF_BIBR], while TDP-43 deletion in Caenorhabditis elegans downregulates histone deacetylase 6 (HDAC6), causing aggregate formation and promotion of the cytotoxicity caused by polyglutamine expanded ataxin-3 [XREF_BIBR]."

22072931

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IndraLab

Statements

TARDBP activates ATXN3. 1 / 1

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