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REST increases the amount of UCHL1. 2 / 3
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"Furthermore, low levels of NRSF/REST in cancer increase the expression and activity of UCHL1, inhibiting its degradation mediated by HIF-1α ubiquitination and consequently increasing the expression of[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Transient overexpression of NRSF reduces endogenous levels of UCHL1 in DMS53 cells, whereas NRSF siRNA transfection increases UCHL1 expression in U87-MG."