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USP29 inhibits MAP3K7. 2 / 2

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"We found that USP29 deregulated the polyubiquitinated state of the k63 TAK1 linkage through deubiquitination, thereby inhibiting TAK1 autophosphorylation and suppressing the activation of the downstream JNK/p38 pathway."

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"For example, USP29 attenuates hepatic ischemia-reperfusion injury by preventing the activation of TAK1 through K63-linked polyubiquitination [21]."

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USP29 inhibits MAP3K7. 2 / 2

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