IndraLab

Statements



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"Silencing of USP54 in colorectal cancer cells decreases their proliferation, invasiveness, and colony-forming capacity, as well as their tumorigenicity, when injected into immunodeficient mice [72] ."

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"Thus, the loss of USP54 significantly reduced CRPC cell proliferation in vivo."

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"USP54 gene disruption significantly inhibited CRPC cell proliferation, both in vitro and in vivo."

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"USP54 silencing suppressed the proliferation of PCa cell lines, both in vitro and in vivo."

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"USP54 depletion suppressed CRPC cell proliferation both in vitro and in vivo."

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"These findings demonstrate that USP54 deficiency restores gefitinib sensitivity in resistant PC9/GR spheroids, reducing their viability and proliferation to levels observed in nonresistant spheroids."