IndraLab

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SCN2A activates sodium(1+). 3 / 3
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"Three recognized sodium channel gene EEs are caused by mutations in SCN8A, SCN1A (Dravet syndrome), SCN2A, and SCN8A."
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"A similar phenomenon has been observed in benign familial neonatal-infantile seizures caused by mutations in the SCN2A gene, encoding the sodium channel Nav1.2, which is expressed transiently during d[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Mutations in SCN2A are thought to cause epileptic seizures by allowing an excess of sodium to enter affected neurons, causing the neurons to aberrantly fire action potentials."
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