IndraLab

Statements


USP38 activates JUNB. 4 / 4
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"USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein."

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"USP38 is induced by TCR signaling and in turn promotes JunB stabilization to specifically regulate Th2 cell differentiation."

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"Altogether, our data suggest that TCR-induced USP38 specifically blocks JunB protein turnover, thus promoting Th2 cytokines production."

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"The restoration study also confirmed the specificity of USP38 in TCR-induced JunB instead of c-Jun stability (Fig. 10 A)."