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USP49 deubiquitinates FKBP5. 1 / 1

1 |

"Mechanistically, USP49 deubiquitinates and stabilizes FKBP51, which in turn enhances PHLPP's capability to dephosphorylate AKT Furthermore, USP49 inhibited pancreatic cancer cell proliferation and enhanced cellular response to gemcitabine in a FKBP51-AKT-dependent manner."

28363942

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USP49 deubiquitinates FKBP5. 1 / 1

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