IndraLab

Statements

EVO decreases the amount of USP4. 2 / 2

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"As shown in Fig. 4A, EVO significantly reduced USP4, SOX9, OCT4 and CD133 expression in a dose-dependent manner, indicating EVO could regulate CRC cell stemness."

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"Importantly, EVO inhibited USP4 expression and reduced the levels of SOX9, OCT4, and CD133.These results suggest that EVO may relieve the regulation of CRC stemness by inhibiting USP4 deubiquitination and stabilizing SOX9."

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INDRA sources:

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IndraLab

Statements

EVO decreases the amount of USP4. 2 / 2

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