IndraLab

Statements


COPS6 inhibits TRIM21. 2 / 2
| 2

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"Together, these results indicate that CSN6 promoted TRIM21 degradation is dependent on TRIM21 self ubiquitination via K48 ubiquitin linkage."

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"We have shown that CSN6 promotes ubiquitin-dependent degradation of TRIM21, and it is then possible that CSN6 can regulate FASN stability through TRIM21 as well."