IndraLab

Statements

USP22 inhibits Death. 3 / 3
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"Ma et al. found that ubiquitin-specific peptidase 22 (USP22) inhibits cardiomyocyte death induced by ferroptosis in myocardial I/R injury via the SIRT1/p53/SLC7A11 axis, providing a novel therapeutic target for the treatment [83]."
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"Overexpression of USP22 could inhibit ferroptotic cardiomyocyte death to protect against IRI (102)."
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"A recent study shows that the expression of USP22 protein, a kind of deubiquitinase, can inhibit ferroptotic cardiomyocyte death through the SIRT1/p53/SLC7A11 axis and further protect against myocardial ischemia/reperfusion injury [64]."
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