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ATM phosphorylates BAP1. 12 / 12
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"The nuclear localized deubiquitylating enzyme BAP1 XREF_BIBR, XREF_BIBR, which is responsible for histone modification in transcription regulation XREF_BIBR, XREF_BIBR, can be phosphorylated by Ataxia telangiectasia mutated (ATM) and participates in DNA double-strand break (DSB) repair through regulating histone 2A and H2AX ubiquitylation XREF_BIBR, XREF_BIBR."
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"The DUB BAP1 is also recruited to DNA damage sites and is phosphorylated by ATM (Ismail et al. 2014; Yu et al. 2014)."
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"BAP1 is phosphorylated by ATM, which promotes its recruitment to the DSB site."
33230107
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"It was further demonstrated that both of the catalytic activity and the phosphorylation of BAP1 by ATM is required for efficient assembly of the homologous recombination (HR) factors BRCA1 and RAD51 at the DSB loci (Fig. xref ) xref ."
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"The role of BAP1 phosphorylation by ATM and possibly by ATR under replication stress conditions is still unknown and needs to be addressed in future studies."
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"The role of BAP1 phosphorylation by ATM and possibly by ATR under replication stress conditions is still unknown and needs to be addressed in future studies."
37009801
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"Intriguingly, BAP1 is directly phosphorylated by ATM upon DNA damage and is required for efficient assembly of homologous recombination (HR) repair factors BRCA1 and RAD51 at IR-induced foci to promote repair of DNA double-strand breaks (DSBs) ."
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"BAP1 is phosphorylated by ATM kinase, and promotes repair of DSBs through PARP dependent recruitment of the polycomb DUB complex to DNA damage sites [XREF_BIBR]."
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"BAP1 is phosphorylated by ATM kinase, and promotes repair of DSBs through PARP-dependent recruitment of the polycomb DUB complex to DNA damage sites [ xref ]."
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"BAP1 was shown to mediate poly (ADP-ribose)-dependent recruitment of the Polycomb-repressive deubiquitinase complex (PR-DUB) to sites of DNA damage, was phosphorylated by ATM, and promoted repair of DNA double-strand breaks ."
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"Intriguingly, BAP1 is directly phosphorylated by ATM upon DNA damage and is required for efficient assembly of homologous recombination (HR) repair factors BRCA1 and RAD51 at IR-induced foci to promote repair of DNA double-strand breaks (DSBs) xref , xref ."
32541668
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"Interestingly, during the cellular response to DNA double-strand breaks (DSBs) induced by UV irradiation or DNA damaging agents xref , BAP1 could be phosphorylated by DDR kinase ATM, and then recruited to the chromatin near DSB sites xref , xref ."
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