IndraLab

Statements


USP37 decreases the amount of ERK. 2 / 2
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"As shown in Fig. 4, A–C, the knockdown of USP37 decreased ERK1/2 protein levels but not ERK1/2 mRNA levels."

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"Additionally, CDK1/2 inhibitors decreased ERK1/2 protein levels in control cells but not USP37-depleted cells, suggesting that CDK2 may regulate ERK1/2 protein levels through USP37 (Fig. 6 B; and Fig. S3, B and C)."