IndraLab

Statements


USP50 inhibits XRCC6. 4 / 4
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"Interestingly, USP50 associates with the Ku70 protein and reduces the half-life of Ku70 protein."

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"Thus, we hypothesize that USP50 mediated Ku70 degradation might be through targeting a ubiquitin E3 ligase that ubiquitinates and degrades Ku70."

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"USP50 reduces Ku70 protein stability without affecting its mRNA levels."

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"These data suggest that USP50 reduces Ku70 protein stability."